US Medical Term · conditions
Sickle Cell Disease
Enfermedad de células falciformes
Also: Anemia de células falciformes (regional variant)
What it means
Sickle cell disease (SCD) is a group of inherited red blood cell disorders. In SCD there is a problem with hemoglobin, a protein in red blood cells that carries oxygen throughout the body: the hemoglobin forms into stiff rods within the red blood cells and changes their shape. The cells are supposed to be disc-shaped, but instead they are crescent, or sickle, shaped. Many of them burst apart as they move through the blood vessels, so a person may not have enough red blood cells, a condition called anemia. The sickle-shaped cells can stick to vessel walls and cause a blockage, and the lack of oxygen can cause attacks of sudden, severe pain, called pain crises. People with SCD are born with two sickle cell genes, one from each parent.
Sickle Cell Disease in Spanish
- Spanish term
- Enfermedad de células falciformes
- Gender and article
- feminine: la enfermedad de células falciformes
- Pronunciation
- en-fehr-meh-DAHD deh SEH-loo-lahs fahl-see-FOR-mehs
| Other Spanish terms | Where it is used | Note |
|---|---|---|
| anemia de células falciformes | General | Other name given at the end of the National Cancer Institute's Spanish dictionary entry for enfermedad de células falciformes. |
| drepanocitosis | General | Other name given in the same National Cancer Institute entry; the Spanish dictionary has an entry for it as a medical term. |
| anemia falciforme | General | Listed by MedlinePlus en español among the other names on its Enfermedad de células falciformes page. |
Enfermedad de células falciformes is feminine: la enfermedad de células falciformes. It is the title of the MedlinePlus en español page and the headword in the National Cancer Institute's Spanish dictionary. That dictionary adds that the disease is also called anemia de células falciformes, drepanocitemia and drepanocitosis, and the Spanish dictionary has an entry for drepanocitosis as a medical term. In English, the National Cancer Institute likewise says the disease is also called sickle cell anemia.
MedlinePlus en español describes the cells as having the shape de medialuna o de hoz (crescent or sickle) and calls them células falciformes. Sickle cell trait, having one sickle cell gene, is rasgo de células falciformes; the same page also writes rasgo drepanocítico. A pain crisis is una crisis de dolor, red blood cells are glóbulos rojos, and hemoglobina and anemia are close to their English forms.
Phrases for an appointment
What a patient or a clinician might say, in English and Spanish:
| Who | English | Spanish |
|---|---|---|
| Patient | I have sickle cell disease, and I am having a pain crisis. | Tengo enfermedad de células falciformes y estoy teniendo una crisis de dolor. |
| Clinician | Where is the pain, and when did it start? | ¿Dónde tiene el dolor y cuándo empezó? |
| Patient | It started this morning, in my back and my legs. | Empezó esta mañana, en la espalda y las piernas. |
| Clinician | Have you had to go to the hospital for a pain crisis before? | ¿Ha tenido que ir al hospital antes por una crisis de dolor? |
| Clinician | Do you have sickle cell disease or sickle cell trait? | ¿Tiene enfermedad de células falciformes o rasgo de células falciformes? |
| Patient | I have the trait, and so does my partner. Can our baby be tested? | Tengo el rasgo, y mi pareja también. ¿Le pueden hacer la prueba a nuestro bebé? |
| Clinician | A blood test can show if you have the disease or the trait. | Un examen de sangre puede mostrar si tiene la enfermedad o el rasgo. |
| Patient | I feel very tired. Could it be from the anemia? | Siento mucho cansancio. ¿Puede ser por la anemia? |
In 9 languages
| Language | Term |
|---|---|
| English | Sickle Cell Disease |
| Spanish (Español) | Enfermedad de células falciformes |
| Chinese (中文) | 鐮刀型紅血球疾病 |
| Korean (한국어) | 겸상적혈구병 |
| Vietnamese (Tiếng Việt) | Bệnh hồng cầu hình liềm |
| Filipino (Tagalog) | Sickle Cell Disease |
| Portuguese (Português) | Doença falciforme |
| Thai (ภาษาไทย) | โรคเม็ดเลือดแดงรูปเคียว |
| Japanese (日本語) | 鎌状赤血球症 |
Where you'll see it
Related ICD-10-CM category
ICD-10-CM code: D57 → Sickle-cell disordersRelated terms
Your right to an interpreter in the United States
If English is not your primary language and you have difficulty communicating in English, you may need an interpreter or a translated document when you visit a doctor or dentist, go to the emergency room or pick up a prescription. The U.S. Department of Health and Human Services Office for Civil Rights states that two federal laws, Title VI of the Civil Rights Act of 1964 and Section 1557 of the Affordable Care Act, require programs that receive its funding to provide language access services free of charge.
You can ask when you make the appointment or at the front desk: "I need an interpreter, please." «Necesito un intérprete, por favor.»
More terms: Blood and immune system
All terms in this area: Blood and immune system — Sangre y sistema inmunitario
Sources
- Sickle Cell Disease — MedlinePlus, National Library of Medicine
- Enfermedad de células falciformes — MedlinePlus en español, Biblioteca Nacional de Medicina
- sickle cell disease — NCI Dictionary of Cancer Terms — National Cancer Institute (NCI), NIH
- enfermedad de células falciformes — Diccionario de cáncer del NCI — Instituto Nacional del Cáncer (NCI), NIH
- drepanocitosis — Diccionario de la lengua española — Real Academia Española / ASALE
- Limited English Proficiency (LEP): Your Right to Language Assistance Services — U.S. Department of Health and Human Services, Office for Civil Rights
This page is a language reference. It is not medical advice.
Last reviewed: October 8, 2026