ICD-10-CM · Chapter 3 · D50-D89
D57 Sickle-cell disorders
Excludes 1 (cannot be coded together)
- other hemoglobinopathies (D58.-)
Use Additional Code
- code for any associated fever (R50.81)
Subcodes
Each subcode links to a detail page with full clinical annotations.
| Code | Description | Billable |
|---|---|---|
| D57..0 | Hb-SS disease with crisis | No |
| D57..00 | Hb-SS disease with crisis, unspecified | Yes |
| D57..01 | Hb-SS disease with acute chest syndrome | Yes |
| D57..02 | Hb-SS disease with splenic sequestration | Yes |
| D57..03 | Hb-SS disease with cerebral vascular involvement | Yes |
| D57..04 | Hb-SS disease with dactylitis | Yes |
| D57..09 | Hb-SS disease with crisis with other specified complication | Yes |
| D57..1 | Sickle-cell disease without crisis | Yes |
| D57..2 | Sickle-cell/Hb-C disease | No |
| D57..20 | Sickle-cell/Hb-C disease without crisis | Yes |
| D57..21 | Sickle-cell/Hb-C disease with crisis | No |
| D57..211 | Sickle-cell/Hb-C disease with acute chest syndrome | Yes |
| D57..212 | Sickle-cell/Hb-C disease with splenic sequestration | Yes |
| D57..213 | Sickle-cell/Hb-C disease with cerebral vascular involvement | Yes |
| D57..214 | Sickle-cell/Hb-C disease with dactylitis | Yes |
| D57..218 | Sickle-cell/Hb-C disease with crisis with other specified complication | Yes |
| D57..219 | Sickle-cell/Hb-C disease with crisis, unspecified | Yes |
| D57..3 | Sickle-cell trait | Yes |
| D57..4 | Sickle-cell thalassemia | No |
| D57..40 | Sickle-cell thalassemia without crisis | Yes |
| D57..41 | Sickle-cell thalassemia, unspecified, with crisis | No |
| D57..411 | Sickle-cell thalassemia, unspecified, with acute chest syndrome | Yes |
| D57..412 | Sickle-cell thalassemia, unspecified, with splenic sequestration | Yes |
| D57..413 | Sickle-cell thalassemia, unspecified, with cerebral vascular involvement | Yes |
| D57..414 | Sickle-cell thalassemia, unspecified, with dactylitis | Yes |
| D57..418 | Sickle-cell thalassemia, unspecified, with crisis with other specified complication | Yes |
| D57..419 | Sickle-cell thalassemia, unspecified, with crisis | Yes |
| D57..42 | Sickle-cell thalassemia beta zero without crisis | Yes |
| D57..43 | Sickle-cell thalassemia beta zero with crisis | No |
| D57..431 | Sickle-cell thalassemia beta zero with acute chest syndrome | Yes |
| D57..432 | Sickle-cell thalassemia beta zero with splenic sequestration | Yes |
| D57..433 | Sickle-cell thalassemia beta zero with cerebral vascular involvement | Yes |
| D57..434 | Sickle-cell thalassemia beta zero with dactylitis | Yes |
| D57..438 | Sickle-cell thalassemia beta zero with crisis with other specified complication | Yes |
| D57..439 | Sickle-cell thalassemia beta zero with crisis, unspecified | Yes |
| D57..44 | Sickle-cell thalassemia beta plus without crisis | Yes |
| D57..45 | Sickle-cell thalassemia beta plus with crisis | No |
| D57..451 | Sickle-cell thalassemia beta plus with acute chest syndrome | Yes |
| D57..452 | Sickle-cell thalassemia beta plus with splenic sequestration | Yes |
| D57..453 | Sickle-cell thalassemia beta plus with cerebral vascular involvement | Yes |
| D57..454 | Sickle-cell thalassemia beta plus with dactylitis | Yes |
| D57..458 | Sickle-cell thalassemia beta plus with crisis with other specified complication | Yes |
| D57..459 | Sickle-cell thalassemia beta plus with crisis, unspecified | Yes |
| D57..8 | Other sickle-cell disorders | No |
| D57..80 | Other sickle-cell disorders without crisis | Yes |
| D57..81 | Other sickle-cell disorders with crisis | No |
| D57..811 | Other sickle-cell disorders with acute chest syndrome | Yes |
| D57..812 | Other sickle-cell disorders with splenic sequestration | Yes |
| D57..813 | Other sickle-cell disorders with cerebral vascular involvement | Yes |
| D57..814 | Other sickle-cell disorders with dactylitis | Yes |
| D57..818 | Other sickle-cell disorders with crisis with other specified complication | Yes |
| D57..819 | Other sickle-cell disorders with crisis, unspecified | Yes |
Plain-language term for this code
The following entry in the US Medical Glossary corresponds to ICD-10-CM category D57:
- Sickle Cell Disease — Enfermedad de células falciformes
Last reviewed: September 2026