ICD-10-CM · Chapter 21 · Z00-Z99
Z15 Genetic susceptibility to disease
Includes
- confirmed abnormal gene
Excludes 1 (cannot be coded together)
- chromosomal anomalies (Q90-Q99)
Use Additional Code
- code, if applicable, for any associated family history of the disease (Z80-Z84)
Subcodes
Subcodes are listed below for reference. Detail pages are not available for chapters 11–22.
| Code | Description | Billable |
|---|---|---|
| Z15..0 | Genetic susceptibility to malignant neoplasm | No |
| Z15..01 | Genetic susceptibility to malignant neoplasm of breast | Yes |
| Z15..02 | Genetic susceptibility to malignant neoplasm of ovary | Yes |
| Z15..03 | Genetic susceptibility to malignant neoplasm of prostate | Yes |
| Z15..04 | Genetic susceptibility to malignant neoplasm of endometrium | Yes |
| Z15..05 | Genetic susceptibility to malignant neoplasm of fallopian tube(s) | Yes |
| Z15..06 | Genetic susceptibility to malignant neoplasm of digestive system | No |
| Z15..060 | Genetic susceptibility to colorectal cancer | Yes |
| Z15..068 | Genetic susceptibility to other malignant neoplasm of digestive system | Yes |
| Z15..07 | Genetic susceptibility to malignant neoplasm of urinary tract | Yes |
| Z15..09 | Genetic susceptibility to other malignant neoplasm | Yes |
| Z15..1 | Genetic susceptibility to epilepsy and neurodevelopmental disorders | Yes |
| Z15..2 | Genetic susceptibility to obesity | Yes |
| Z15..3 | Genetic susceptibility to kidney disease | Yes |
| Z15..8 | Genetic susceptibility to other disease | No |
| Z15..81 | Genetic susceptibility to multiple endocrine neoplasia [MEN] | Yes |
| Z15..89 | Genetic susceptibility to other disease | Yes |
Last reviewed: September 2026