Emergency: 119
AMDA-IMIC

Z16 Resistance to antimicrobial drugs

Category / Non-billable header 23 subcodes

Block: Resistance to antimicrobial drugs (Z16)

Excludes 1 (cannot be coded together)

  • Methicillin resistant Staphylococcus aureus infection (A49.02)
  • Methicillin resistant Staphylococcus aureus pneumonia (J15.212)
  • Sepsis due to Methicillin resistant Staphylococcus aureus (A41.02)

Notes

  • The codes in this category are provided for use as additional codes to identify the resistance and non-responsiveness of a condition to antimicrobial drugs.

Code First

  • the infection

Subcodes

Subcodes are listed below for reference. Detail pages are not available for chapters 11–22.

Code Description Billable
Z16..1 Resistance to beta lactam antibiotics No
Z16..10 Resistance to unspecified beta lactam antibiotics Yes
Z16..11 Resistance to penicillins Yes
Z16..12 Extended spectrum beta lactamase (ESBL) resistance Yes
Z16..13 Resistance to carbapenem Yes
Z16..19 Resistance to other specified beta lactam antibiotics Yes
Z16..2 Resistance to other antibiotics No
Z16..20 Resistance to unspecified antibiotic Yes
Z16..21 Resistance to vancomycin Yes
Z16..22 Resistance to vancomycin related antibiotics Yes
Z16..23 Resistance to quinolones and fluoroquinolones Yes
Z16..24 Resistance to multiple antibiotics Yes
Z16..29 Resistance to other single specified antibiotic Yes
Z16..3 Resistance to other antimicrobial drugs No
Z16..30 Resistance to unspecified antimicrobial drugs Yes
Z16..31 Resistance to antiparasitic drug(s) Yes
Z16..32 Resistance to antifungal drug(s) Yes
Z16..33 Resistance to antiviral drug(s) Yes
Z16..34 Resistance to antimycobacterial drug(s) No
Z16..341 Resistance to single antimycobacterial drug Yes
Z16..342 Resistance to multiple antimycobacterial drugs Yes
Z16..35 Resistance to multiple antimicrobial drugs Yes
Z16..39 Resistance to other specified antimicrobial drug Yes

Last reviewed: September 2026