ICD-10-CM · Chapter 18 · R00-R99
R53 Malaise and fatigue
Subcodes
Subcodes are listed below for reference. Detail pages are not available for chapters 11–22.
| Code | Description | Billable |
|---|---|---|
| R53..0 | Neoplastic (malignant) related fatigue | Yes |
| R53..1 | Weakness | Yes |
| R53..2 | Functional quadriplegia | Yes |
| R53..8 | Other malaise and fatigue | No |
| R53..81 | Other malaise | Yes |
| R53..82 | Chronic fatigue, unspecified | Yes |
| R53..83 | Other fatigue | Yes |
Plain-language terms for this code
The following entries in the US Medical Glossary correspond to ICD-10-CM category R53:
Last reviewed: September 2026