Emergency: 119
AMDA-IMIC

C49 Malignant neoplasm of other connective and soft tissue

Category / Non-billable header 23 subcodes

Block: Malignant neoplasms of mesothelial and soft tissue (C45-C49)

Includes

  • malignant neoplasm of blood vessel
  • malignant neoplasm of bursa
  • malignant neoplasm of cartilage
  • malignant neoplasm of fascia
  • malignant neoplasm of fat
  • malignant neoplasm of ligament, except uterine
  • malignant neoplasm of lymphatic vessel
  • malignant neoplasm of muscle
  • malignant neoplasm of synovia
  • malignant neoplasm of tendon (sheath)

Excludes 1 (cannot be coded together)

  • malignant neoplasm of cartilage (of):
  • articular (C40-C41)
  • larynx (C32.3)
  • nose (C30.0)
  • malignant neoplasm of connective tissue of breast (C50.-)

Excludes 2 (not included here)

  • Kaposi's sarcoma of soft tissue (C46.1)
  • malignant neoplasm of heart (C38.0)
  • malignant neoplasm of peripheral nerves and autonomic nervous system (C47.-)
  • malignant neoplasm of peritoneum (C48.2)
  • malignant neoplasm of retroperitoneum (C48.0)
  • malignant neoplasm of uterine ligament (C57.3)
  • mesothelioma (C45.-)

Subcodes

Each subcode links to a detail page with full clinical annotations.

Code Description Billable
C49..0 Malignant neoplasm of connective and soft tissue of head, face and neck Yes
C49..1 Malignant neoplasm of connective and soft tissue of upper limb, including shoulder No
C49..10 Malignant neoplasm of connective and soft tissue of unspecified upper limb, including shoulder Yes
C49..11 Malignant neoplasm of connective and soft tissue of right upper limb, including shoulder Yes
C49..12 Malignant neoplasm of connective and soft tissue of left upper limb, including shoulder Yes
C49..2 Malignant neoplasm of connective and soft tissue of lower limb, including hip No
C49..20 Malignant neoplasm of connective and soft tissue of unspecified lower limb, including hip Yes
C49..21 Malignant neoplasm of connective and soft tissue of right lower limb, including hip Yes
C49..22 Malignant neoplasm of connective and soft tissue of left lower limb, including hip Yes
C49..3 Malignant neoplasm of connective and soft tissue of thorax Yes
C49..4 Malignant neoplasm of connective and soft tissue of abdomen Yes
C49..5 Malignant neoplasm of connective and soft tissue of pelvis Yes
C49..6 Malignant neoplasm of connective and soft tissue of trunk, unspecified Yes
C49..8 Malignant neoplasm of overlapping sites of connective and soft tissue Yes
C49..9 Malignant neoplasm of connective and soft tissue, unspecified Yes
C49..A Gastrointestinal stromal tumor No
C49..A0 Gastrointestinal stromal tumor, unspecified site Yes
C49..A1 Gastrointestinal stromal tumor of esophagus Yes
C49..A2 Gastrointestinal stromal tumor of stomach Yes
C49..A3 Gastrointestinal stromal tumor of small intestine Yes
C49..A4 Gastrointestinal stromal tumor of large intestine Yes
C49..A5 Gastrointestinal stromal tumor of rectum Yes
C49..A9 Gastrointestinal stromal tumor of other sites Yes

Last reviewed: September 2026