Z21 Asymptomatic human immunodeficiency virus [HIV] infection status

Billable

Block: Persons with potential health hazards related to communicable diseases (Z20-Z29)

Includes

  • HIV positive NOS

Excludes 1 (cannot be coded together)

  • acquired immunodeficiency syndrome (B20)
  • contact with human immunodeficiency virus [HIV] (Z20.6)
  • exposure to human immunodeficiency virus [HIV] (Z20.6)
  • human immunodeficiency virus [HIV] disease (B20)
  • inconclusive laboratory evidence of human immunodeficiency virus [HIV] (R75)

Code First

  • Human immunodeficiency virus [HIV] disease complicating pregnancy, childbirth and the puerperium, if applicable (O98.7-)
This category is a complete, billable diagnosis code.

No additional specificity is required — submit Z21 directly on claims and documentation without a subcode extension.

Last reviewed: September 2026