I21 Acute myocardial infarction

Category / Non-billable header 17 subcodes

Block: Ischemic heart diseases (I20-I25)

Includes

  • cardiac infarction
  • coronary (artery) embolism
  • coronary (artery) occlusion
  • coronary (artery) rupture
  • coronary (artery) thrombosis
  • infarction of heart, myocardium, or ventricle
  • myocardial infarction specified as acute or with a stated duration of 4 weeks (28 days) or less from onset

Excludes 2 (not included here)

  • old myocardial infarction (I25.2)
  • postmyocardial infarction syndrome (I24.1)
  • subsequent type 1 myocardial infarction (I22.-)

Use Additional Code

  • code, if applicable, to identify:
  • exposure to environmental tobacco smoke (Z77.22)
  • history of tobacco dependence (Z87.891)
  • occupational exposure to environmental tobacco smoke (Z57.31)
  • status post administration of tPA (rtPA) in a different facility within the last 24 hours prior to admission to current facility (Z92.82)
  • tobacco dependence (F17.-)
  • tobacco use (Z72.0)

Subcodes

Each subcode links to a detail page with full clinical annotations.

Code Description Billable
I21..0 ST elevation (STEMI) myocardial infarction of anterior wall No
I21..01 ST elevation (STEMI) myocardial infarction involving left main coronary artery Yes
I21..02 ST elevation (STEMI) myocardial infarction involving left anterior descending coronary artery Yes
I21..09 ST elevation (STEMI) myocardial infarction involving other coronary artery of anterior wall Yes
I21..1 ST elevation (STEMI) myocardial infarction of inferior wall No
I21..11 ST elevation (STEMI) myocardial infarction involving right coronary artery Yes
I21..19 ST elevation (STEMI) myocardial infarction involving other coronary artery of inferior wall Yes
I21..2 ST elevation (STEMI) myocardial infarction of other sites No
I21..21 ST elevation (STEMI) myocardial infarction involving left circumflex coronary artery Yes
I21..29 ST elevation (STEMI) myocardial infarction involving other sites Yes
I21..3 ST elevation (STEMI) myocardial infarction of unspecified site Yes
I21..4 Non-ST elevation (NSTEMI) myocardial infarction Yes
I21..9 Acute myocardial infarction, unspecified Yes
I21..A Other type of myocardial infarction No
I21..A1 Myocardial infarction type 2 Yes
I21..A9 Other myocardial infarction type Yes
I21..B Myocardial infarction with coronary microvascular dysfunction Yes

Last reviewed: September 2026